Our Collaborative Research Center (CRC) includes 20 subprojects that contribute to four project areas with different focal points.
Research area A investigates the molecular and cellular determinants of neural resources, through the exploration of synaptic connections and small neural networks at the microscopic level. Research area B focuses on neural resources at the mesoscopic level, i.e., through the connectivity across brain areas. Research area C is dedicated to the macroscopic level and investigates, for example, how neural resources are assigned to tasks. The service projects (Z) support all subprojects with specialized methodology and know-how – from microscopic visualization of active synapses to tau imaging in “super agers”.
Molecular & cellular determinants of neural resources
Research area A
Project A01 – A09
A03
Neural circuits underlying behaviour-dependent brain state transitions: Resource allocation for optimized memory processing in health and disease
A04
Cognitive enhancement by the anti- ageing hormone Klotho – from molecular mechanisms to interventions
A05
Extracellular matrix integrity as neural resource of memory precision and cognitive flexibility
Meso-scale determinants of neural resources
Research area B
Project B02 – B07
B02
Mobilizing reserve in episodic memory in individuals with Alzheimer`s disease pathology
B03
From Alzheimer’s Disease to SuperAgeing: A Cross-Species Study on Grid Cells as a central resource for Memory and Navigation
B04
Synaptic density, MTL circuit function and microvascular plasticity in aging and SuperAging
B05
Mobilisation of attentional resources in multiple object and feaure tracking: training and perturbation of circuits
New
B07
Circuit-specific improvements of mnemonic discrimination in the rodent and human entorhino-hippocampal subnetworks
Macro-scale principles of neural resources and resource allocation
Research area C
Project C01 – C05
Scientific Service Projects
Research area Z