Great news: On Monday, June 1st, 2026, Professor Kamil Uludag (Sunnybrook Research Institute & Department for Medical Biophysics, University of Toronto) will be a guest in our CRC Lecture Series.
Who: Kamil Uludag, Sunnybrook Research Institute & Department for Medical Biophysics, University of Toronto
When: Monday, June 1st, 2026 / 1:00 pm
Where: DZNE, room 121
Title: Translating MRI Methods for Perfusion and Anatomy from 3T and 7T into Clinical Applications
Abstract: This talk presents a translational framework bridging methodological developments in perfusion and structural MRI across 3T and 7T, with applications in neurodegenerative and neuropsychiatric diseases, as well as brain tumors. At 3T, we have developed and validated advanced perfusion approaches, including multi-echo DSC and hybrid acquisitions, alongside quantitative structural imaging methods sensitive to tissue microstructure. Together, these techniques enable more robust and biologically specific characterization of vascular and anatomical changes, with demonstrated clinical utility – for example, in assessing tumor heterogeneity and treatment response, as well as in evaluating targeted neuromodulation and blood–brain barrier modulation following MR-guided focused ultrasound.
Building on this foundation, we translate these approaches to 7T, leveraging increased signal-to-noise ratio and susceptibility contrast to achieve high-resolution perfusion, structural, and functional imaging. This enables interrogation of microvascular and microstructural alterations even at the level of cortical layers and subcortical circuits, providing new insights into disease mechanisms. Collectively, these developments illustrate how coordinated advances across field strengths can yield precise imaging biomarkers and support emerging therapeutic strategies in neurodegenerative, neuropsychiatric, and neuro-oncological disorders.
Guests are very welcome.