{"id":40608,"date":"2026-06-25T12:56:47","date_gmt":"2026-06-25T10:56:47","guid":{"rendered":"https:\/\/sfb1436.de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/"},"modified":"2026-09-07T12:57:16","modified_gmt":"2026-09-07T10:57:16","slug":"differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions","status":"publish","type":"post","link":"https:\/\/sfb1436.de\/de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/","title":{"rendered":"Differential and state-dependent effects of the GluN2A-selective positive allosteric modulator GNE-5729 on executive functions"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"40608\" class=\"elementor elementor-40608 elementor-40603\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-20880b2 e-flex e-con-boxed e-con e-parent\" data-id=\"20880b2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-84745f9 elementor-widget elementor-widget-text-editor\" data-id=\"84745f9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em>Johannes Lauer,\u00a0Julia Poppke,\u00a0Thomas Nickl-Jockschat,\u00a0Daniela C. Dieterich,\u00a0Markus Fendt\u00a0&amp;\u00a0Samia Afzal<\/em><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5e27deb elementor-widget elementor-widget-text-editor\" data-id=\"5e27deb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"journal\">\r\n\r\n<i>Neuropsychopharmacology (2026)<\/i>\r\n\r\n<\/div><br>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Johannes Lauer,\u00a0Julia Poppke,\u00a0Thomas Nickl-Jockschat,\u00a0Daniela C. Dieterich,\u00a0Markus Fendt\u00a0&amp;\u00a0Samia Afzal Neuropsychopharmacology (2026)<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[198],"tags":[1973],"class_list":["post-40608","post","type-post","status-publish","format-standard","hentry","category-a01-de","tag-https-doi-org-10-1038-s41386-026-02476-1"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>GluN2A-selective positive allosteric<\/title>\n<meta name=\"description\" content=\"Differential and state-dependent effects of the GluN2A-selective positive allosteric modulator GNE-5729 on executive functions\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sfb1436.de\/de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"GluN2A-selective positive allosteric\" \/>\n<meta property=\"og:description\" content=\"Differential and state-dependent effects of the GluN2A-selective positive allosteric modulator GNE-5729 on executive functions\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sfb1436.de\/de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/\" \/>\n<meta property=\"og:site_name\" content=\"SFB1436\" \/>\n<meta property=\"article:published_time\" content=\"2026-06-25T10:56:47+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-09-07T10:57:16+00:00\" \/>\n<meta name=\"author\" content=\"redakteur\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Verfasst von\" \/>\n\t<meta name=\"twitter:data1\" content=\"redakteur\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\\\/\"},\"author\":{\"name\":\"redakteur\",\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/#\\\/schema\\\/person\\\/c0ef0d254080f73ef2aa76e57caa6d12\"},\"headline\":\"Differential and state-dependent effects of the GluN2A-selective positive allosteric modulator GNE-5729 on executive functions\",\"datePublished\":\"2026-06-25T10:56:47+00:00\",\"dateModified\":\"2026-09-07T10:57:16+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\\\/\"},\"wordCount\":30,\"publisher\":{\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/#organization\"},\"keywords\":[\"https:\\\/\\\/doi.org\\\/10.1038\\\/s41386-026-02476-1\"],\"articleSection\":[\"A01\"],\"inLanguage\":\"de\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\\\/\",\"url\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\\\/\",\"name\":\"GluN2A-selective positive allosteric\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/#website\"},\"datePublished\":\"2026-06-25T10:56:47+00:00\",\"dateModified\":\"2026-09-07T10:57:16+00:00\",\"description\":\"Differential and state-dependent effects of the GluN2A-selective positive allosteric modulator GNE-5729 on executive functions\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\\\/#breadcrumb\"},\"inLanguage\":\"de\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/sfb1436.de\\\/de\\\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Startseite\",\"item\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Differential and state-dependent effects of the GluN2A-selective positive allosteric modulator GNE-5729 on executive functions\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/#website\",\"url\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/\",\"name\":\"SFB1436\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"de\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/#organization\",\"name\":\"Otto-von-Guericke Universit\u00e4t Medizinische Fakult\u00e4t Institut f\u00fcr Kognitive Neurologie und Demenzforschung\",\"url\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"de\",\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/sfb1436.de\\\/wp-content\\\/uploads\\\/2021\\\/12\\\/logo-sfb.png\",\"contentUrl\":\"https:\\\/\\\/sfb1436.de\\\/wp-content\\\/uploads\\\/2021\\\/12\\\/logo-sfb.png\",\"width\":1244,\"height\":820,\"caption\":\"Otto-von-Guericke Universit\u00e4t Medizinische Fakult\u00e4t Institut f\u00fcr Kognitive Neurologie und Demenzforschung\"},\"image\":{\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/sfb1436.de\\\/de\\\/#\\\/schema\\\/person\\\/c0ef0d254080f73ef2aa76e57caa6d12\",\"name\":\"redakteur\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"GluN2A-selective positive allosteric","description":"Differential and state-dependent effects of the GluN2A-selective positive allosteric modulator GNE-5729 on executive functions","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/sfb1436.de\/de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/","og_locale":"de_DE","og_type":"article","og_title":"GluN2A-selective positive allosteric","og_description":"Differential and state-dependent effects of the GluN2A-selective positive allosteric modulator GNE-5729 on executive functions","og_url":"https:\/\/sfb1436.de\/de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/","og_site_name":"SFB1436","article_published_time":"2026-06-25T10:56:47+00:00","article_modified_time":"2026-09-07T10:57:16+00:00","author":"redakteur","twitter_card":"summary_large_image","twitter_misc":{"Verfasst von":"redakteur"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/sfb1436.de\/de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/#article","isPartOf":{"@id":"https:\/\/sfb1436.de\/de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/"},"author":{"name":"redakteur","@id":"https:\/\/sfb1436.de\/de\/#\/schema\/person\/c0ef0d254080f73ef2aa76e57caa6d12"},"headline":"Differential and state-dependent effects of the GluN2A-selective positive allosteric modulator GNE-5729 on executive functions","datePublished":"2026-06-25T10:56:47+00:00","dateModified":"2026-09-07T10:57:16+00:00","mainEntityOfPage":{"@id":"https:\/\/sfb1436.de\/de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/"},"wordCount":30,"publisher":{"@id":"https:\/\/sfb1436.de\/de\/#organization"},"keywords":["https:\/\/doi.org\/10.1038\/s41386-026-02476-1"],"articleSection":["A01"],"inLanguage":"de"},{"@type":"WebPage","@id":"https:\/\/sfb1436.de\/de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/","url":"https:\/\/sfb1436.de\/de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/","name":"GluN2A-selective positive allosteric","isPartOf":{"@id":"https:\/\/sfb1436.de\/de\/#website"},"datePublished":"2026-06-25T10:56:47+00:00","dateModified":"2026-09-07T10:57:16+00:00","description":"Differential and state-dependent effects of the GluN2A-selective positive allosteric modulator GNE-5729 on executive functions","breadcrumb":{"@id":"https:\/\/sfb1436.de\/de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/#breadcrumb"},"inLanguage":"de","potentialAction":[{"@type":"ReadAction","target":["https:\/\/sfb1436.de\/de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/sfb1436.de\/de\/differential-and-state-dependent-effects-of-the-glun2a-selective-positive-allosteric-modulator-gne-5729-on-executive-functions\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Startseite","item":"https:\/\/sfb1436.de\/de\/"},{"@type":"ListItem","position":2,"name":"Differential and state-dependent effects of the GluN2A-selective positive allosteric modulator GNE-5729 on executive functions"}]},{"@type":"WebSite","@id":"https:\/\/sfb1436.de\/de\/#website","url":"https:\/\/sfb1436.de\/de\/","name":"SFB1436","description":"","publisher":{"@id":"https:\/\/sfb1436.de\/de\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/sfb1436.de\/de\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"de"},{"@type":"Organization","@id":"https:\/\/sfb1436.de\/de\/#organization","name":"Otto-von-Guericke Universit\u00e4t Medizinische Fakult\u00e4t Institut f\u00fcr Kognitive Neurologie und Demenzforschung","url":"https:\/\/sfb1436.de\/de\/","logo":{"@type":"ImageObject","inLanguage":"de","@id":"https:\/\/sfb1436.de\/de\/#\/schema\/logo\/image\/","url":"https:\/\/sfb1436.de\/wp-content\/uploads\/2021\/12\/logo-sfb.png","contentUrl":"https:\/\/sfb1436.de\/wp-content\/uploads\/2021\/12\/logo-sfb.png","width":1244,"height":820,"caption":"Otto-von-Guericke Universit\u00e4t Medizinische Fakult\u00e4t Institut f\u00fcr Kognitive Neurologie und Demenzforschung"},"image":{"@id":"https:\/\/sfb1436.de\/de\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/sfb1436.de\/de\/#\/schema\/person\/c0ef0d254080f73ef2aa76e57caa6d12","name":"redakteur"}]}},"_links":{"self":[{"href":"https:\/\/sfb1436.de\/de\/wp-json\/wp\/v2\/posts\/40608","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sfb1436.de\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sfb1436.de\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sfb1436.de\/de\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/sfb1436.de\/de\/wp-json\/wp\/v2\/comments?post=40608"}],"version-history":[{"count":1,"href":"https:\/\/sfb1436.de\/de\/wp-json\/wp\/v2\/posts\/40608\/revisions"}],"predecessor-version":[{"id":40609,"href":"https:\/\/sfb1436.de\/de\/wp-json\/wp\/v2\/posts\/40608\/revisions\/40609"}],"wp:attachment":[{"href":"https:\/\/sfb1436.de\/de\/wp-json\/wp\/v2\/media?parent=40608"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sfb1436.de\/de\/wp-json\/wp\/v2\/categories?post=40608"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sfb1436.de\/de\/wp-json\/wp\/v2\/tags?post=40608"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}