{"id":33786,"date":"2026-07-09T11:06:06","date_gmt":"2026-07-09T09:06:06","guid":{"rendered":"https:\/\/sfb1436.de\/unsere-projekte\/archiv-sfb-1436-1-2021-2024\/bdnf-abhaengige-neuroplastizitaet-als-neuronale-ressource-der-kortiko-hippokampalen-interaktion\/"},"modified":"2026-07-09T11:06:06","modified_gmt":"2026-07-09T09:06:06","slug":"bdnf-abhaengige-neuroplastizitaet-als-neuronale-ressource-der-kortiko-hippokampalen-interaktion","status":"publish","type":"page","link":"https:\/\/sfb1436.de\/de\/projekte\/archiv-sfb-1436-1-2021-2024\/bdnf-abhaengige-neuroplastizitaet-als-neuronale-ressource-der-kortiko-hippokampalen-interaktion\/","title":{"rendered":"BDNF-abh\u00e4ngige Neuroplastizit\u00e4t als neuronale Ressource der kortiko-hippokampalen Interaktion"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"33786\" class=\"elementor elementor-33786 elementor-33533\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bdba1e8 e-con-full h-0 e-flex e-con e-child\" data-id=\"bdba1e8\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-65ab371 title-box elementor-widget elementor-widget-heading\" data-id=\"65ab371\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">A06<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-997ac2a e-flex e-con-boxed e-con e-parent\" data-id=\"997ac2a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-761aa39 e-con-full e-flex e-con e-child\" data-id=\"761aa39\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4b214b5 elementor-widget elementor-widget-image\" data-id=\"4b214b5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"713\" height=\"768\" src=\"https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/05\/abstract_A06_web.jpg\" class=\"attachment-large size-large wp-image-10369\" alt=\"BDNF-abh\u00e4ngige Neuroplastizit\u00e4t als neuronale Ressource der kortiko-hippokampalen Interaktion\" srcset=\"https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/05\/abstract_A06_web.jpg 713w, https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/05\/abstract_A06_web-279x300.jpg 279w\" sizes=\"(max-width: 713px) 100vw, 713px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-16c5128 e-con-full e-flex e-con e-child\" data-id=\"16c5128\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5412ece elementor-widget elementor-widget-text-editor\" data-id=\"5412ece\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Die flexible Steuerung von Verhalten und Verhaltens\u00e4nderungen durch Lernprozesse erfordert die neuronale Interaktion verschiedener Hirnareale. Die Interaktionen zwischen sensorischen und pr\u00e4frontalen Cortex-Arealen mit dem Hippocampus haben f\u00fcr diese Prozesse eine hervorgehobene Bedeutung. Wir untersuchen in unserem Projekt, wie durch Krankheit oder Altern bedingte St\u00f6rungen in einem der interagierenden Hirnareale durch neuroplastische Prozesse in den anderen Hirnregionen kompensiert werden k\u00f6nnen. Hierzu untersuchen wir, wie sich die optogenetisch kontrollierte Freisetzung des plastizit\u00e4tssteuernden neurotrophen Faktors BDNF in corticalen Arealen oder im Hippocampus auf die cortico-hippocampale Interaktion auswirkt, und wie dadurch gesteuerte Lernprozesse in Mausmodellen erleichtert werden k\u00f6nnen, die durch Alterungsprozesse oder die Alzheimersche Krankheit gest\u00f6rt wurden.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f2d2956 e-flex e-con-boxed e-con e-parent\" data-id=\"f2d2956\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-00dec2b elementor-widget elementor-widget-eael-creative-button\" data-id=\"00dec2b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-creative-button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t        <div class=\"eael-creative-button-wrapper\">\n\n            <a class=\"eael-creative-button eael-creative-button--default eael-cb-icon-position-\" href=\"#focus\" data-text=\"\">\n            \t    \n                <div class=\"creative-button-inner\">\n\n                    \n                    <span class=\"cretive-button-text\">Unsere Forschung<\/span>\n\n                                    <\/div>\n\t                        <\/a>\n        <\/div>\n        \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0176041 elementor-widget elementor-widget-eael-creative-button\" data-id=\"0176041\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-creative-button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t        <div class=\"eael-creative-button-wrapper\">\n\n            <a class=\"eael-creative-button eael-creative-button--default eael-cb-icon-position-\" href=\"#goals\" data-text=\"\">\n            \t    \n                <div class=\"creative-button-inner\">\n\n                    \n                    <span class=\"cretive-button-text\">Ziele unseres Projektes<\/span>\n\n                                    <\/div>\n\t                        <\/a>\n        <\/div>\n        \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c2ee487 elementor-widget elementor-widget-eael-creative-button\" data-id=\"c2ee487\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-creative-button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t        <div class=\"eael-creative-button-wrapper\">\n\n            <a class=\"eael-creative-button eael-creative-button--default eael-cb-icon-position-\" href=\"#feature\" data-text=\"\">\n            \t    \n                <div class=\"creative-button-inner\">\n\n                    \n                    <span class=\"cretive-button-text\">Blick in die Zukunft<\/span>\n\n                                    <\/div>\n\t                        <\/a>\n        <\/div>\n        \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-068e107 elementor-widget elementor-widget-eael-creative-button\" data-id=\"068e107\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-creative-button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t        <div class=\"eael-creative-button-wrapper\">\n\n            <a class=\"eael-creative-button eael-creative-button--default eael-cb-icon-position-\" href=\"#publications\" data-text=\"\">\n            \t    \n                <div class=\"creative-button-inner\">\n\n                    \n                    <span class=\"cretive-button-text\">Publikationen<\/span>\n\n                                    <\/div>\n\t                        <\/a>\n        <\/div>\n        \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4962557 e-flex e-con-boxed e-con e-parent\" data-id=\"4962557\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6ac76a7 elementor-widget elementor-widget-heading\" data-id=\"6ac76a7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Gruppenleitung<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6224d27 text-center elementor-widget elementor-widget-awsm-team\" data-id=\"6224d27\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"awsm-team.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"awsm-team-3555\" class=\"awsm-grid-wrapper\">\n\t\t\n\t\t<div class=''>\n\t\t<div class=\"gridder awsm-grid drawer-style style-1 grid-2-col \">\n\t\t\t\t\t\t<div id=\"awsm-member-3555-3325\" class=\"awsm-grid-list awsm-grid-card awsm-team-item awsm-scale-anm awsm-all awsm-68 awsm-30\" data-griddercontent=\"#awsm-grid-content-3325\">\n\t\t\t\t\t<span class=\"awsm-team-link-control awsm-grid-list-item awsm-grid-list-item-3325\" data-info=\"3325\">\n\t\t\t\t\t\t<figure>\n\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"1000\" src=\"https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/02\/Lessmann-800x1000.jpg\" class=\"attachment-awsm_team size-awsm_team wp-post-image\" alt=\"CRC 1436 member Volkmar Le\u00dfmann\" \/>\t\t\t\t\t\t\t<figcaption>\n\t\t\t\t\t\t\t\t<div class=\"awsm-personal-info\"><span><\/span><h3>Prof. Dr. Dr. med. Volkmar Le\u00dfmann<\/h3><\/div>\t\t\t\t\t\t\t<\/figcaption>\n\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-3555-3371\" class=\"awsm-grid-list awsm-grid-card awsm-team-item awsm-scale-anm awsm-all awsm-68 awsm-30\" data-griddercontent=\"#awsm-grid-content-3371\">\n\t\t\t\t\t<span class=\"awsm-team-link-control awsm-grid-list-item awsm-grid-list-item-3371\" data-info=\"3371\">\n\t\t\t\t\t\t<figure>\n\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"785\" src=\"https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/01\/no-image-men-4.png\" class=\"attachment-awsm_team size-awsm_team wp-post-image\" alt=\"picture is coming soon\" \/>\t\t\t\t\t\t\t<figcaption>\n\t\t\t\t\t\t\t\t<div class=\"awsm-personal-info\"><span><\/span><h3>Prof. Dr. Frank Ohl<\/h3><\/div>\t\t\t\t\t\t\t<\/figcaption>\n\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<div class=\"awsm-grid-expander style-1\">\n\t\t\t\t\t\t<div id=\"awsm-member-info-3555-3325\"  class=\"awsm-grid-expander style-1\">\n\t\t\t\t<div class=\"awsm-detailed-info\" id=\"awsm-grid-content-3325\">\n\t\t\t\t\t<div class=\"awsm-details\">\n\t\t\t\t\t\t<div class=\"awsm-personal-details\">\n\t\t\t\t\t\t\t<div class=\"awsm-content-scrollbar\">\n\t\t\t\t\t\t\t\t<span><\/span><h2>Prof. Dr. Dr. med. Volkmar Le\u00dfmann<\/h2>\n<p class=\"wp-block-paragraph\">Volkmar Le\u00dfmann is the Director of the Institute of Physiology at the Medical Faculty of the Otto-von-Guericke-University Magdeburg. His research is focussed on molecular and cellular mechanisms of synaptic plasticity in health and disease. Using combined electrophysiological and advanced fluorescence microscopy techniques, his group investigates how neuromodulatory transmitters like dopamine and neurotrophins like BDNF shape synaptic transmission in neuronal circuits of the mouse hippocampus, amygdala, and prefrontal cortex, and how this affects learning in vivo. In collaboration with Psychiatrists, Neurologists, and Sports scientists from Magdeburg and Jena, his team further investigates the role of BDNF as a biomarker in patients of major depressive disorder (MDD), schizophrenia and dementia. Together with the group of Frank Ohl from the LIN, his research addresses optogenetically driven BDNF regulation of neuronal circuits in maladapted cortico-hippocampal interactions that are involved in Alzheimer\u2019s disease and fear learning.<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"awsm-personal-contact-info\">\n\t\t\t\t\t   <div class=\"awsm-contact-details\"><p><a href=\"http:\/\/www.med.ovgu.de\/\" target=\"_blank\">Otto von Guericke University Magdeburg, Medical Faculty<\/a><\/p><p><a href=\"https:\/\/sfb1436.de\/projects\/neural-resource-mediated-by-bdnf-dependent-neuroplasticity-of-cortico-hippocampal-interactions\/\" target=\"_blank\"><b>A06 <\/b> Neural resource mediated by BDNF-dependent neuroplasticity of cortico-hippocampal interactions<\/a><\/p><\/div><div class=\"awsm-social-icons\"><span><a href=\"mailto:volkmar.lessmann@med.ovgu.de\"><i class=\"awsm-icon-mail\" aria-hidden=\"true\"><\/i><\/a><\/span><span><a href=\"tel:+49-391-67-15885\" target=\"_blank\"><i class=\"awsm-icon-phone\" aria-hidden=\"true\"><\/i><\/a><\/span><span><a href=\"http:\/\/iphy.med.ovgu.de\/\" target=\"_blank\"><i class=\"awsm-icon-link\" aria-hidden=\"true\"><\/i><\/a><\/span><\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-info-3555-3371\"  class=\"awsm-grid-expander style-1\">\n\t\t\t\t<div class=\"awsm-detailed-info\" id=\"awsm-grid-content-3371\">\n\t\t\t\t\t<div class=\"awsm-details\">\n\t\t\t\t\t\t<div class=\"awsm-personal-details\">\n\t\t\t\t\t\t\t<div class=\"awsm-content-scrollbar\">\n\t\t\t\t\t\t\t\t<span><\/span><h2>Prof. Dr. Frank Ohl<\/h2>\n<p class=\"wp-block-paragraph\">Frank Ohl is Director of the Department &#8222;Systems Physiology of Learning&#8220; at the Leibniz Institute for Neurobiology Magdeburg and is Professor of &#8222;Neurobiology&#8220; at the Institute of Biology of the Faculty of Natural sciences of the Otto-von-Guericke University Magdeburg. His background is neurophysiology and physics. He has developed rodent modes for cognitive processes (including concept learning and category formation) und investigates neuronal dynamics during learning using electrophysiological, optical and optogenetic methods. In collaboration with mathematicians and computer scientists he also develops neurocomputational models of experimentally investigated neuronal processes and helps with the advancement of machine learning strategies using novel neuro-inspired algorithms.<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"awsm-personal-contact-info\">\n\t\t\t\t\t   <div class=\"awsm-contact-details\"><p><a href=\"https:\/\/www.lin-magdeburg.de\/\" target=\"_blank\">Leibniz Institute for Neurobiology (LIN) Magdeburg<\/a><\/p><p><a href=\"https:\/\/sfb1436.de\/projects\/neural-resource-mediated-by-bdnf-dependent-neuroplasticity-of-cortico-hippocampal-interactions\/\" target=\"_blank\"><b>A06 <\/b> Neural resource mediated by BDNF-dependent neuroplasticity of cortico-hippocampal interactions<\/a><\/p><\/div><div class=\"awsm-social-icons\"><span><a href=\"mailto:Frank.Ohl@lin-magdeburg.de\"><i class=\"awsm-icon-mail\" aria-hidden=\"true\"><\/i><\/a><\/span><span><a href=\"tel:+49-391-6263-95481\" target=\"_blank\"><i class=\"awsm-icon-phone\" aria-hidden=\"true\"><\/i><\/a><\/span><span><a href=\"https:\/\/www.lin-magdeburg.de\/forschung\/abteilung-systemphysiologie-des-lernens\" target=\"_blank\"><i class=\"awsm-icon-link\" aria-hidden=\"true\"><\/i><\/a><\/span><\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t<\/div>\n\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fc5ff7c elementor-widget elementor-widget-heading\" data-id=\"fc5ff7c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Gruppenmitglieder<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-55087c7 text-center elementor-widget elementor-widget-awsm-team\" data-id=\"55087c7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"awsm-team.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"awsm-team-3556\" class=\"awsm-grid-wrapper\">\n\t\t\n\t\t<div class=''>\n\t\t<div class=\"gridder awsm-grid drawer-style style-1 grid-5-col \">\n\t\t\t\t\t\t<div id=\"awsm-member-3556-3169\" class=\"awsm-grid-list awsm-grid-card awsm-team-item awsm-scale-anm awsm-all awsm-90 awsm-40\" data-griddercontent=\"#awsm-grid-content-3169\">\n\t\t\t\t\t<span class=\"awsm-team-link-control awsm-grid-list-item awsm-grid-list-item-3169\" data-info=\"3169\">\n\t\t\t\t\t\t<figure>\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"1000\" src=\"https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/05\/20211102-0858_Thomas-Endres-800x1000.jpg\" class=\"attachment-awsm_team size-awsm_team wp-post-image\" alt=\"SFB 1436 Mitglied Thomas Endres\" \/>\t\t\t\t\t\t\t<figcaption>\n\t\t\t\t\t\t\t\t<div class=\"awsm-personal-info\"><span><\/span><h3>Dr. Thomas Endres<\/h3><\/div>\t\t\t\t\t\t\t<\/figcaption>\n\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-3556-3202\" class=\"awsm-grid-list awsm-grid-card awsm-team-item awsm-scale-anm awsm-all awsm-90 awsm-40\" data-griddercontent=\"#awsm-grid-content-3202\">\n\t\t\t\t\t<span class=\"awsm-team-link-control awsm-grid-list-item awsm-grid-list-item-3202\" data-info=\"3202\">\n\t\t\t\t\t\t<figure>\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"780\" src=\"https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/01\/no-image-woman-2.png\" class=\"attachment-awsm_team size-awsm_team wp-post-image\" alt=\"picture is coming soon\" \/>\t\t\t\t\t\t\t<figcaption>\n\t\t\t\t\t\t\t\t<div class=\"awsm-personal-info\"><span><\/span><h3>Jana K\u00f6hler<\/h3><\/div>\t\t\t\t\t\t\t<\/figcaption>\n\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-3556-3354\" class=\"awsm-grid-list awsm-grid-card awsm-team-item awsm-scale-anm awsm-all awsm-90 awsm-40\" data-griddercontent=\"#awsm-grid-content-3354\">\n\t\t\t\t\t<span class=\"awsm-team-link-control awsm-grid-list-item awsm-grid-list-item-3354\" data-info=\"3354\">\n\t\t\t\t\t\t<figure>\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"785\" src=\"https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/01\/no-image-men-4.png\" class=\"attachment-awsm_team size-awsm_team wp-post-image\" alt=\"Platzhalter SFB 1436 Magdeburg Mitglieder kein Foto\" \/>\t\t\t\t\t\t\t<figcaption>\n\t\t\t\t\t\t\t\t<div class=\"awsm-personal-info\"><span><\/span><h3>Dr. Michael Lippert<\/h3><\/div>\t\t\t\t\t\t\t<\/figcaption>\n\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-3556-3362\" class=\"awsm-grid-list awsm-grid-card awsm-team-item awsm-scale-anm awsm-all awsm-90 awsm-40\" data-griddercontent=\"#awsm-grid-content-3362\">\n\t\t\t\t\t<span class=\"awsm-team-link-control awsm-grid-list-item awsm-grid-list-item-3362\" data-info=\"3362\">\n\t\t\t\t\t\t<figure>\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"780\" src=\"https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/01\/no-image-woman-2.png\" class=\"attachment-awsm_team size-awsm_team wp-post-image\" alt=\"picture is coming soon\" \/>\t\t\t\t\t\t\t<figcaption>\n\t\t\t\t\t\t\t\t<div class=\"awsm-personal-info\"><span><\/span><h3>Dr. Susanne Meis<\/h3><\/div>\t\t\t\t\t\t\t<\/figcaption>\n\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-3556-3367\" class=\"awsm-grid-list awsm-grid-card awsm-team-item awsm-scale-anm awsm-all awsm-90 awsm-40\" data-griddercontent=\"#awsm-grid-content-3367\">\n\t\t\t\t\t<span class=\"awsm-team-link-control awsm-grid-list-item awsm-grid-list-item-3367\" data-info=\"3367\">\n\t\t\t\t\t\t<figure>\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"785\" src=\"https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/01\/no-image-men-4.png\" class=\"attachment-awsm_team size-awsm_team wp-post-image\" alt=\"Platzhalter SFB 1436 Magdeburg Mitglieder kein Foto\" \/>\t\t\t\t\t\t\t<figcaption>\n\t\t\t\t\t\t\t\t<div class=\"awsm-personal-info\"><span><\/span><h3>Dr. Thomas Munsch<\/h3><\/div>\t\t\t\t\t\t\t<\/figcaption>\n\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-3556-22653\" class=\"awsm-grid-list awsm-grid-card awsm-team-item awsm-scale-anm awsm-all\" data-griddercontent=\"#awsm-grid-content-22653\">\n\t\t\t\t\t<span class=\"awsm-team-link-control awsm-grid-list-item awsm-grid-list-item-22653\" data-info=\"22653\">\n\t\t\t\t\t\t<figure>\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"1000\" src=\"https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/01\/no-image-men-2-800x1000.png\" class=\"attachment-awsm_team size-awsm_team wp-post-image\" alt=\"Platzhalter SFB 1436 Magdeburg Mitglieder kein Foto\" \/>\t\t\t\t\t\t\t<figcaption>\n\t\t\t\t\t\t\t\t<div class=\"awsm-personal-info\"><span><\/span><h3>Maxime Picard<\/h3><\/div>\t\t\t\t\t\t\t<\/figcaption>\n\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-3556-3483\" class=\"awsm-grid-list awsm-grid-card awsm-team-item awsm-scale-anm awsm-all awsm-90 awsm-40\" data-griddercontent=\"#awsm-grid-content-3483\">\n\t\t\t\t\t<span class=\"awsm-team-link-control awsm-grid-list-item awsm-grid-list-item-3483\" data-info=\"3483\">\n\t\t\t\t\t\t<figure>\n\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"780\" src=\"https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/01\/no-image-woman-1.png\" class=\"attachment-awsm_team size-awsm_team wp-post-image\" alt=\"Platzhalter SFB 1436 Magdeburg Mitglieder kein Foto\" \/>\t\t\t\t\t\t\t<figcaption>\n\t\t\t\t\t\t\t\t<div class=\"awsm-personal-info\"><span><\/span><h3>Alisa Vlasenko<\/h3><\/div>\t\t\t\t\t\t\t<\/figcaption>\n\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<div class=\"awsm-grid-expander style-1\">\n\t\t\t\t\t\t<div id=\"awsm-member-info-3556-3169\"  class=\"awsm-grid-expander style-1\">\n\t\t\t\t<div class=\"awsm-detailed-info\" id=\"awsm-grid-content-3169\">\n\t\t\t\t\t<div class=\"awsm-details\">\n\t\t\t\t\t\t<div class=\"awsm-personal-details\">\n\t\t\t\t\t\t\t<div class=\"awsm-content-scrollbar\">\n\t\t\t\t\t\t\t\t<span><\/span><h2>Dr. Thomas Endres<\/h2>\n<p class=\"wp-block-paragraph\">coming soon<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"awsm-personal-contact-info\">\n\t\t\t\t\t   <div class=\"awsm-contact-details\"><p><a href=\"http:\/\/www.med.ovgu.de\/\" target=\"_blank\">Otto von Guericke University Magdeburg, Medical Faculty<\/a><\/p><p><a href=\"https:\/\/sfb1436.de\/projects\/neural-resource-mediated-by-bdnf-dependent-neuroplasticity-of-cortico-hippocampal-interactions\/\" target=\"_blank\"><b>A06 <\/b> Neural resource mediated by BDNF-dependent neuroplasticity of cortico-hippocampal interactions<\/a><\/p><\/div><div class=\"awsm-social-icons\"><span><a href=\"mailto:thomas.endres@med.ovgu.de\"><i class=\"awsm-icon-mail\" aria-hidden=\"true\"><\/i><\/a><\/span><span><a href=\"http:\/\/www.zebik.ovgu.de\/\" target=\"_blank\"><i class=\"awsm-icon-link\" aria-hidden=\"true\"><\/i><\/a><\/span><\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-info-3556-3202\"  class=\"awsm-grid-expander style-1\">\n\t\t\t\t<div class=\"awsm-detailed-info\" id=\"awsm-grid-content-3202\">\n\t\t\t\t\t<div class=\"awsm-details\">\n\t\t\t\t\t\t<div class=\"awsm-personal-details\">\n\t\t\t\t\t\t\t<div class=\"awsm-content-scrollbar\">\n\t\t\t\t\t\t\t\t<span><\/span><h2>Jana K\u00f6hler<\/h2>\n<p class=\"wp-block-paragraph\">coming soon<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"awsm-personal-contact-info\">\n\t\t\t\t\t   <div class=\"awsm-contact-details\"><p><a href=\"https:\/\/www.dzne.de\/\" target=\"_blank\">German Center for Neurodegenerative Diseases, Magdeburg<\/a><\/p><p><a href=\"https:\/\/sfb1436.de\/projects\/neural-resource-mediated-by-bdnf-dependent-neuroplasticity-of-cortico-hippocampal-interactions\/\" target=\"_blank\"><b>A06 <\/b> Neural resource mediated by BDNF-dependent neuroplasticity of cortico-hippocampal interactions<\/a><\/p><\/div><div class=\"awsm-social-icons\"><span><a href=\"mailto:jana.koehler@med.ovgu.de\"><i class=\"awsm-icon-mail\" aria-hidden=\"true\"><\/i><\/a><\/span><span><a href=\"http:\/\/iphy.med.ovgu.de\/\" target=\"_blank\"><i class=\"awsm-icon-link\" aria-hidden=\"true\"><\/i><\/a><\/span><\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-info-3556-3354\"  class=\"awsm-grid-expander style-1\">\n\t\t\t\t<div class=\"awsm-detailed-info\" id=\"awsm-grid-content-3354\">\n\t\t\t\t\t<div class=\"awsm-details\">\n\t\t\t\t\t\t<div class=\"awsm-personal-details\">\n\t\t\t\t\t\t\t<div class=\"awsm-content-scrollbar\">\n\t\t\t\t\t\t\t\t<span><\/span><h2>Dr. Michael Lippert<\/h2>\n<p class=\"wp-block-paragraph\">coming soon<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"awsm-personal-contact-info\">\n\t\t\t\t\t   <div class=\"awsm-contact-details\"><p><a href=\"https:\/\/www.lin-magdeburg.de\/\" target=\"_blank\">Leibniz Institute for Neurobiology (LIN) Magdeburg<\/a><\/p><\/div><div class=\"awsm-social-icons\"><span><a href=\"mailto:mlippert@lin-magdeburg.de\" target=\"_blank\"><i class=\"awsm-icon-mail\" aria-hidden=\"true\"><\/i><\/a><\/span><span><a href=\"https:\/\/www.lin-magdeburg.de\/forschung\/abteilung-systemphysiologie-des-lernens\" target=\"_blank\"><i class=\"awsm-icon-link\" aria-hidden=\"true\"><\/i><\/a><\/span><\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-info-3556-3362\"  class=\"awsm-grid-expander style-1\">\n\t\t\t\t<div class=\"awsm-detailed-info\" id=\"awsm-grid-content-3362\">\n\t\t\t\t\t<div class=\"awsm-details\">\n\t\t\t\t\t\t<div class=\"awsm-personal-details\">\n\t\t\t\t\t\t\t<div class=\"awsm-content-scrollbar\">\n\t\t\t\t\t\t\t\t<span><\/span><h2>Dr. Susanne Meis<\/h2>\n<p class=\"wp-block-paragraph\">coming soon<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"awsm-personal-contact-info\">\n\t\t\t\t\t   <div class=\"awsm-contact-details\"><p><a href=\"http:\/\/www.med.ovgu.de\/\" target=\"_blank\">Otto von Guericke University Magdeburg, Medical Faculty<\/a><\/p><p><a href=\"https:\/\/sfb1436.de\/projects\/neural-resource-mediated-by-bdnf-dependent-neuroplasticity-of-cortico-hippocampal-interactions\/\" target=\"_blank\"><b>A06 <\/b> Neural resource mediated by BDNF-dependent neuroplasticity of cortico-hippocampal interactions<\/a><\/p><\/div><div class=\"awsm-social-icons\"><span><a href=\"mailto:susanne.meis@med.ovgu.de\"><i class=\"awsm-icon-mail\" aria-hidden=\"true\"><\/i><\/a><\/span><span><a href=\"http:\/\/iphy.med.ovgu.de\/\" target=\"_blank\"><i class=\"awsm-icon-link\" aria-hidden=\"true\"><\/i><\/a><\/span><\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-info-3556-3367\"  class=\"awsm-grid-expander style-1\">\n\t\t\t\t<div class=\"awsm-detailed-info\" id=\"awsm-grid-content-3367\">\n\t\t\t\t\t<div class=\"awsm-details\">\n\t\t\t\t\t\t<div class=\"awsm-personal-details\">\n\t\t\t\t\t\t\t<div class=\"awsm-content-scrollbar\">\n\t\t\t\t\t\t\t\t<span><\/span><h2>Dr. Thomas Munsch<\/h2>\n<p class=\"wp-block-paragraph\">coming soon<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"awsm-personal-contact-info\">\n\t\t\t\t\t   <div class=\"awsm-contact-details\"><p><a href=\"http:\/\/www.med.ovgu.de\/\" target=\"_blank\">Otto von Guericke University Magdeburg, Medical Faculty<\/a><\/p><p><a href=\"https:\/\/sfb1436.de\/projects\/neural-resource-mediated-by-bdnf-dependent-neuroplasticity-of-cortico-hippocampal-interactions\/\" target=\"_blank\"><b>A06 <\/b> Neural resource mediated by BDNF-dependent neuroplasticity of cortico-hippocampal interactions<\/a><\/p><\/div><div class=\"awsm-social-icons\"><span><a href=\"mailto:thomas.munsch@med.ovgu.de\"><i class=\"awsm-icon-mail\" aria-hidden=\"true\"><\/i><\/a><\/span><span><a href=\"http:\/\/iphy.med.ovgu.de\/\" target=\"_blank\"><i class=\"awsm-icon-link\" aria-hidden=\"true\"><\/i><\/a><\/span><\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-info-3556-22653\"  class=\"awsm-grid-expander style-1\">\n\t\t\t\t<div class=\"awsm-detailed-info\" id=\"awsm-grid-content-22653\">\n\t\t\t\t\t<div class=\"awsm-details\">\n\t\t\t\t\t\t<div class=\"awsm-personal-details\">\n\t\t\t\t\t\t\t<div class=\"awsm-content-scrollbar\">\n\t\t\t\t\t\t\t\t<span><\/span><h2>Maxime Picard<\/h2>\n<p class=\"wp-block-paragraph\">Ich bin Doktorand in der Gruppe von Prof. Le\u00dfmann am Institut f\u00fcr Physiologie der Otto-von-Guericke-Universit\u00e4t Magdeburg. Ich habe meinen Masterabschluss in Neurowissenschaften an der Universit\u00e4t Caen Normandie, Frankreich, erworben und meine Masterarbeit an der Universit\u00e4t Helsinki, Finnland, angefertigt, wo ich elektrophysiologische Patch-Clamp-Ableitungen an Interneuronen in der basso-lateralen Amygdala-Region des M\u00e4usegehirns durchf\u00fchrte. Ich bin Mitglied des CRC1436-Projekts A06: Neural resource mediated by BDNF-dependent neuroplasticity of cortico-hippocampal interactions. Ich verwende die Patch-Clamp-Elektrophysiologie-Technik, um die funktionellen Interaktionen entlang der Achse Hippocampus-Pr\u00e4frontal-Cortex zu untersuchen. Ein weiteres Ziel meiner Forschung ist die Untersuchung der Rolle von BDNF bei der Gestaltung der synaptischen \u00dcbertragung entlang der oben genannten Achse.<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"awsm-personal-contact-info\">\n\t\t\t\t\t   <div class=\"awsm-contact-details\"><p><a href=\"http:\/\/www.med.ovgu.de\/\" target=\"_blank\">Otto von Guericke University Magdeburg, Medical Faculty<\/a><\/p><p><a href=\"https:\/\/sfb1436.de\/projects\/archive-sfb-1436-1-2021-2024\/neural-resource-mediated-by-bdnf-dependent-neuroplasticity-of-cortico-hippocampal-interactions\/\" target=\"_blank\"><b>A06<\/b> Neural resource mediated by BDNF- dependent neuroplasticity of cortico- hippocampal interactions<\/a><\/p><\/div><div class=\"awsm-social-icons\"><span><a href=\"mailto:maxime.picard@med.ovgu.de\"><i class=\"awsm-icon-mail\" aria-hidden=\"true\"><\/i><\/a><\/span><span><a href=\"http:\/\/iphy.med.ovgu.de\/\" target=\"_blank\"><i class=\"awsm-icon-link\" aria-hidden=\"true\"><\/i><\/a><\/span><\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t\t<div id=\"awsm-member-info-3556-3483\"  class=\"awsm-grid-expander style-1\">\n\t\t\t\t<div class=\"awsm-detailed-info\" id=\"awsm-grid-content-3483\">\n\t\t\t\t\t<div class=\"awsm-details\">\n\t\t\t\t\t\t<div class=\"awsm-personal-details\">\n\t\t\t\t\t\t\t<div class=\"awsm-content-scrollbar\">\n\t\t\t\t\t\t\t\t<span><\/span><h2>Alisa Vlasenko<\/h2>\n<p class=\"wp-block-paragraph\">Coming soon<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"awsm-personal-contact-info\">\n\t\t\t\t\t   <div class=\"awsm-contact-details\"><p><a href=\"https:\/\/www.lin-magdeburg.de\/\" target=\"_blank\">Leibniz Institute for Neurobiology (LIN) Magdeburg<\/a><\/p><p><a href=\"https:\/\/sfb1436.de\/projects\/neural-resource-mediated-by-bdnf-dependent-neuroplasticity-of-cortico-hippocampal-interactions\/\" target=\"_blank\"><b>A06 <\/b> Neural resource mediated by BDNF-dependent neuroplasticity of cortico-hippocampal interactions<\/a><\/p><\/div><div class=\"awsm-social-icons\"><span><a href=\"mailto:Alisa.Vlasenko@lin-magdeburg.de\"><i class=\"awsm-icon-mail\" aria-hidden=\"true\"><\/i><\/a><\/span><span><a href=\"https:\/\/www.lin-magdeburg.de\/forschung\/abteilung-systemphysiologie-des-lernens\" target=\"_blank\"><i class=\"awsm-icon-link\" aria-hidden=\"true\"><\/i><\/a><\/span><\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t<\/div>\n\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c59d935 e-grid e-con-boxed e-con e-parent\" data-id=\"c59d935\" data-element_type=\"container\" data-e-type=\"container\" id=\"focus\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c5c559a e-con-full e-flex e-con e-child\" data-id=\"c5c559a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-8dc45d1 e-con-full e-flex e-con e-child\" data-id=\"8dc45d1\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-be6ff00 elementor-widget elementor-widget-text-editor\" data-id=\"be6ff00\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3 id=\"besteht-ein-zusammenhang-zwischen-der-hirnaktivitat-und-der-ecm-zusammensetzung\" class=\"wp-block-heading has-white-color has-secondary-background-color has-text-color has-background\">Was ist die Rolle neuronaler Interaktionen bei Verhalten, Lernen und kompensatorischer Plastizit\u00e4t?<\/h3>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-15f94d2 e-con-full e-flex e-con e-child\" data-id=\"15f94d2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-53b5e5a elementor-widget elementor-widget-text-editor\" data-id=\"53b5e5a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Gehirne h\u00f6herer Wirbeltiere einschlie\u00dflich des Menschen besitzen eine komplexe Architektur, innerhalb derer lokale neuronale Netzwerke (z.B. des Hippocampus oder corticaler Areale) \u00fcber langreichweitige neuronale Projektionen miteinander verbunden sind. Bisherige Konzeptualisierungen der Funktionsprinzipien dieser Strukturen beruhen auf der Idee einer \u201eArbeitsteilung\u201c zwischen diesen Netzwerken im Sinne der \u00dcbernahme bestimmter Funktionen durch jeweils nur eine der interagierenden Hirnregionen. In diesem Projekt verfolgen wir die Idee von wechselseitiger funktioneller Kompensation, also des \u201eEinspringens\u201c eines der funktionell interagierenden Netzwerke bei Ausfall oder Schw\u00e4chung des anderen Netzwerkes. Die neuronale Implementierung solcher Kompensationsprozesse reorganisiert dabei das Interaktionsgeschehen im globalen Netzwerk und wird (vermutlich) durch (lokal induzierte) synaptische Plastizit\u00e4tsmechanismen gesteuert.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b73d28f e-con-full e-flex e-con e-child\" data-id=\"b73d28f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-a23d948 e-con-full e-flex e-con e-child\" data-id=\"a23d948\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-780c391 elementor-widget elementor-widget-text-editor\" data-id=\"780c391\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3 id=\"matrix-variabilitat-und-kognitive-flexibigenetische-variabilitat-in-ecm-kodierenden-genen\" class=\"wp-block-heading has-white-color has-secondary-background-color has-text-color has-background\">Was ist der neutrotrophe Faktor BDNF?<\/h3>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9ca9249 e-con-full e-flex e-con e-child\" data-id=\"9ca9249\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-17f703e elementor-widget elementor-widget-text-editor\" data-id=\"17f703e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Das neurotrophe Protein BDNF wird aktivit\u00e4tsabh\u00e4ngig an Synapsen glutamaterger Neurone ausgesch\u00fcttet. Es ist eines der Schl\u00fcsselmolek\u00fcle f\u00fcr die gebrauchsabh\u00e4ngige Nivellierung der St\u00e4rke der synaptischen \u00dcbertragung an GABAergen und glutamatergen Synapsen, indem es sowohl synaptische Potenzierung (LTP) als auch synaptische Depression (LTD) \u00fcber gegenl\u00e4ufige Signalkaskaden steuert.\u00a0 W\u00e4hrend die lokale synaptische Regulation durch BDNF zunehmend besser verstanden wird, sind die Mechanismen einer daraus resultierenden Steuerung der Netzwerk-Interaktion zwischen interagierenden Hirnregionen bisher v\u00f6llig unklar.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f4ca8ee e-grid e-con-boxed e-con e-parent\" data-id=\"f4ca8ee\" data-element_type=\"container\" data-e-type=\"container\" id=\"goals\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-5b9a1aa e-con-full e-flex e-con e-child\" data-id=\"5b9a1aa\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-da9021a elementor-widget elementor-widget-text-editor\" data-id=\"da9021a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"die-ziele-unseres-projektes\" class=\"wp-block-heading has-text-align-right has-white-color has-text-color\">Die Ziele unseres Projektes<\/h2>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-bc44fc7 e-con-full e-flex e-con e-child\" data-id=\"bc44fc7\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8b38b24 elementor-widget elementor-widget-text-editor\" data-id=\"8b38b24\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>In diesem Projekt untersuchen wir, ob die neuronale Interaktionsdynamik zwischen corticalen Arealen und dem Hippocampus eine wechselseitige Kompensation von verminderter oder Fehlfunktion in einer Hirnregion durch die andere erlaubt, und ob dieser Kompensationsmechanismus durch optogenetische Kontrolle lokaler BDNF-Aussch\u00fcttung unterst\u00fctzt oder angetrieben werden kann. In allen Projekteilen charakterisieren wir dabei lokale Mechanismen der synaptischen Plastizit\u00e4t durch elektrophysiologische patch-clamp-Ableitungen\u00a0<em>in vitro<\/em>\u00a0und transregionale neuronale Interaktionsdynamiken durch Multikanal-Ableitungen\u00a0<em>in<\/em>\u00a0<em>vivo<\/em>. Im ersten Arbeitspaket charakterisieren wir, wie sich die synaptische Plastizit\u00e4t lokaler Netzwerke und die neuronale Interaktion zwischen corticalen Arealen und Hippocampus bei verschiedenen Lernvorg\u00e4ngen, n\u00e4mlich einem sensorisch gesteuerten r\u00e4umlichen Lernen und bei sogenanntem Angst-Extinktionslernen, \u00e4ndern. In einem zweiten Arbeitspaket untersuchen wir dann, wie synaptische Plastizit\u00e4t und neuronale Interaktionsmuster im Alter und im Rahmen der Alzheimer\u2019schen Erkrankung parallel zu verschlechterten Lern- und Ged\u00e4chtnis-Leistungen f\u00fchren, und ob eine optogenetisch kontrollierte Erh\u00f6hung der BDNF-Aussch\u00fcttung im Hippocampus, die neuronale Interaktion mit den corticalen Arealen sowie die kognitive Leistung wiederherstellen kann. In einem dritten Arbeitspaket untersuchen wir die analoge Fragestellung, diesmal aber durch optogenetische Kontrolle der BDNF-Aussch\u00fcttung in corticalen Arealen und im Hinblick auf die neuronale Interaktion dieser Hirnareale mit dem Hippocampus.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a25be31 e-grid e-con-boxed e-con e-parent\" data-id=\"a25be31\" data-element_type=\"container\" data-e-type=\"container\" id=\"feature\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9b8473c elementor-widget elementor-widget-image\" data-id=\"9b8473c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"469\" src=\"https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/05\/senior-man-playing-puzzle-1024x600.png\" class=\"attachment-large size-large wp-image-12591\" alt=\"senior man playing puzzle\" srcset=\"https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/05\/senior-man-playing-puzzle-1024x600.png 1024w, https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/05\/senior-man-playing-puzzle-300x176.png 300w, https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/05\/senior-man-playing-puzzle-768x450.png 768w, https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/05\/senior-man-playing-puzzle-1600x937.png 1600w, https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/05\/senior-man-playing-puzzle-1536x900.png 1536w, https:\/\/sfb1436.de\/wp-content\/uploads\/2022\/05\/senior-man-playing-puzzle.png 1630w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ed4eb22 e-con-full e-flex e-con e-child\" data-id=\"ed4eb22\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6afe7bc elementor-widget elementor-widget-heading\" data-id=\"6afe7bc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Ein Blick in die Zukunft<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-913fefa elementor-widget elementor-widget-text-editor\" data-id=\"913fefa\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Dieses Projekt hat zum Ziel, die optogenetisch kontrollierte lokale Freisetzung von BDNF als eine Strategie zur Rekrutierung kompensatorischer Plastizit\u00e4t der cortico-hippocampalen Interaktion, die im Alter und bei der Alzheimer\u2019schen Krankheit gest\u00f6rt ist, zu etablieren. Sollte dies gelingen, bietet es sich an, dieselbe Interventions-Strategie auch bei anderen Krankheitsbildern, f\u00fcr die eine St\u00f6rung der cortico-hippocampalen Interaktion typisch ist (wie etwa bei Depression), anzuwenden. Schlie\u00dflich k\u00f6nnte dieser Ansatz dann auch in F\u00e4llen erprobt werden, wo neuronale Interaktionen zwischen anderen Hirnarealen, etwa Cortex und Basalganglien beim Morbus Parkinson, gest\u00f6rt sind.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-70dc309 custom-loop e-flex e-con-boxed e-con e-parent\" data-id=\"70dc309\" data-element_type=\"container\" data-e-type=\"container\" id=\"publications\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a0d0e96 elementor-widget elementor-widget-heading\" data-id=\"a0d0e96\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Publikationen des Projektes A06<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-be2f9ae elementor-arrows-position-outside elementor-widget-tablet__width-inherit elementor-pagination-type-bullets elementor-pagination-position-outside elementor-widget elementor-widget-loop-carousel\" data-id=\"be2f9ae\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;template_id&quot;:28475,&quot;_skin&quot;:&quot;post&quot;,&quot;slides_to_show&quot;:&quot;3&quot;,&quot;slides_to_show_tablet&quot;:&quot;2&quot;,&quot;slides_to_show_mobile&quot;:&quot;1&quot;,&quot;slides_to_scroll&quot;:&quot;1&quot;,&quot;edit_handle_selector&quot;:&quot;.elementor-loop-container&quot;,&quot;speed&quot;:500,&quot;arrows&quot;:&quot;yes&quot;,&quot;pagination&quot;:&quot;bullets&quot;,&quot;image_spacing_custom&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:10,&quot;sizes&quot;:[]},&quot;image_spacing_custom_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;image_spacing_custom_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"loop-carousel.post\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"swiper elementor-loop-container elementor-grid\" role=\"list\" dir=\"ltr\">\n\t\t\t\t<div class=\"swiper-wrapper\" aria-live=\"polite\">\n\t\t<style id=\"loop-28475\">.elementor-28475 .elementor-element.elementor-element-2dae7f0b{--display:flex;--min-height:300px;border-style:solid;--border-style:solid;border-width:1px 1px 1px 1px;--border-top-width:1px;--border-right-width:1px;--border-bottom-width:1px;--border-left-width:1px;border-color:var( --e-global-color-dfa7816 );--border-color:var( --e-global-color-dfa7816 );--padding-top:40px;--padding-bottom:30px;--padding-left:30px;--padding-right:30px;}.elementor-28475 .elementor-element.elementor-element-2dae7f0b:not(.elementor-motion-effects-element-type-background), .elementor-28475 .elementor-element.elementor-element-2dae7f0b > .elementor-motion-effects-container > .elementor-motion-effects-layer{background-color:var( --e-global-color-714baa5 );}.elementor-widget-post-info .elementor-icon-list-item:not(:last-child):after{border-color:var( --e-global-color-text );}.elementor-widget-post-info .elementor-icon-list-icon i{color:var( --e-global-color-primary );}.elementor-widget-post-info .elementor-icon-list-icon svg{fill:var( --e-global-color-primary );}.elementor-widget-post-info .elementor-icon-list-text, .elementor-widget-post-info .elementor-icon-list-text a{color:var( --e-global-color-secondary );}.elementor-widget-post-info .elementor-icon-list-item{font-family:var( --e-global-typography-text-font-family ), Sans-serif;font-weight:var( --e-global-typography-text-font-weight );}.elementor-28475 .elementor-element.elementor-element-32caa965 .elementor-icon-list-icon i{color:var( --e-global-color-dfa7816 );font-size:14px;}.elementor-28475 .elementor-element.elementor-element-32caa965 .elementor-icon-list-icon svg{fill:var( --e-global-color-dfa7816 );--e-icon-list-icon-size:14px;}.elementor-28475 .elementor-element.elementor-element-32caa965 .elementor-icon-list-icon{width:14px;}.elementor-28475 .elementor-element.elementor-element-32caa965 .elementor-icon-list-text, .elementor-28475 .elementor-element.elementor-element-32caa965 .elementor-icon-list-text a{color:var( --e-global-color-dfa7816 );}.elementor-widget-heading .elementor-heading-title{font-family:var( --e-global-typography-primary-font-family ), Sans-serif;font-size:var( --e-global-typography-primary-font-size );font-weight:var( --e-global-typography-primary-font-weight );color:var( --e-global-color-primary );}.elementor-28475 .elementor-element.elementor-element-10759525 .elementor-heading-title{font-family:\"Montserrat\", Sans-serif;font-size:18px;font-weight:500;line-height:24px;color:var( --e-global-color-ae35c5a );}.elementor-widget-theme-post-content{color:var( --e-global-color-text );font-family:var( --e-global-typography-text-font-family ), Sans-serif;font-weight:var( --e-global-typography-text-font-weight );}.elementor-28475 .elementor-element.elementor-element-2d46d3e7{color:var( --e-global-color-dfa7816 );}@media(max-width:1024px){.elementor-widget-heading .elementor-heading-title{font-size:var( --e-global-typography-primary-font-size );}}@media(max-width:767px){.elementor-widget-heading .elementor-heading-title{font-size:var( --e-global-typography-primary-font-size );}}<\/style>\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"28475\" class=\"elementor elementor-28475 swiper-slide e-loop-item e-loop-item-19445 post-19445 post type-post status-publish format-standard hentry category-a06-de category-b06-de tag-https-doi-org-10-1038-s41467-023-43620-5\" data-elementor-post-type=\"elementor_library\" role=\"group\" aria-roledescription=\"slide\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-2dae7f0b custom-loop-item e-flex e-con-boxed e-con e-parent\" data-id=\"2dae7f0b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-32caa965 elementor-widget elementor-widget-post-info\" data-id=\"32caa965\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-7093930 elementor-inline-item\" itemprop=\"datePublished\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-calendar\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M12 192h424c6.6 0 12 5.4 12 12v260c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V204c0-6.6 5.4-12 12-12zm436-44v-36c0-26.5-21.5-48-48-48h-48V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H160V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H48C21.5 64 0 85.5 0 112v36c0 6.6 5.4 12 12 12h424c6.6 0 12-5.4 12-12z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>07. Dez. 2023<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-d102256 elementor-inline-item\" itemprop=\"about\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"icon icon-tag\"><\/i>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-terms\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-post-info__terms-list\">\n\t\t\t\t<a href=\"https:\/\/sfb1436.de\/de\/category\/publikation\/a06-de\/\" class=\"elementor-post-info__terms-list-item\">A06<\/a>, <a href=\"https:\/\/sfb1436.de\/de\/category\/publikation\/b06-de\/\" class=\"elementor-post-info__terms-list-item\">B06<\/a>\t\t\t\t<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-10759525 elementor-widget elementor-widget-heading\" data-id=\"10759525\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\"><a class=\"sfb-doi-link swiper-no-swiping\" href=\"https:\/\/doi.org\/10.1038\/s41467-023-43620-5\" target=\"_blank\" rel=\"noopener noreferrer\">Holistic bursting cells store long-term memory in auditory cortex<\/a><\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d46d3e7 elementor-widget elementor-widget-theme-post-content\" data-id=\"2d46d3e7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"theme-post-content.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n<p class=\"wp-block-paragraph\"><em>Li R, Huang J, Li L, Zhao Z, Liang S, Liang S, Wang M, Liao X, Lyu J, Zhou Z, Wang S, Jin W, Chen H, Holder D, Liu H, Zhang J, Li M, Tang Y, Remy S, Pakan JMP, Chen X, Jia H.\u00a0<\/em><\/p>\n\n\n\n<div class=\"wp-block-uagb-icon-list uagb-block-b08f38f6 uagb-icon-list__outer-wrap uagb-icon-list__layout-vertical\"><div class=\"uagb-icon-list__wrap\">\n<div class=\"wp-block-uagb-icon-list-child uagb-block-644d0ab3 uagb-icon-list-repeater uagb-icon-list__wrapper\"><span class=\"uagb-icon-list__source-wrap\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 384 512\"><path d=\"M256 0v128h128L256 0zM224 128L224 0H48C21.49 0 0 21.49 0 48v416C0 490.5 21.49 512 48 512h288c26.51 0 48-21.49 48-48V160h-127.1C238.3 160 224 145.7 224 128zM272 416h-160C103.2 416 96 408.8 96 400C96 391.2 103.2 384 112 384h160c8.836 0 16 7.162 16 16C288 408.8 280.8 416 272 416zM272 352h-160C103.2 352 96 344.8 96 336C96 327.2 103.2 320 112 320h160c8.836 0 16 7.162 16 16C288 344.8 280.8 352 272 352zM288 272C288 280.8 280.8 288 272 288h-160C103.2 288 96 280.8 96 272C96 263.2 103.2 256 112 256h160C280.8 256 288 263.2 288 272z\"><\/path><\/svg><\/span><span class=\"uagb-icon-list__label\"><strong>Nature Communications (2023)<\/strong><\/span><\/div>\n<\/div><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"28475\" class=\"elementor elementor-28475 swiper-slide e-loop-item e-loop-item-17580 post-17580 post type-post status-publish format-standard hentry category-a06-de tag-https-doi-org-10-1007-s00702-023-02618-5-de\" data-elementor-post-type=\"elementor_library\" role=\"group\" aria-roledescription=\"slide\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-2dae7f0b custom-loop-item e-flex e-con-boxed e-con e-parent\" data-id=\"2dae7f0b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-32caa965 elementor-widget elementor-widget-post-info\" data-id=\"32caa965\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-7093930 elementor-inline-item\" itemprop=\"datePublished\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-calendar\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M12 192h424c6.6 0 12 5.4 12 12v260c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V204c0-6.6 5.4-12 12-12zm436-44v-36c0-26.5-21.5-48-48-48h-48V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H160V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H48C21.5 64 0 85.5 0 112v36c0 6.6 5.4 12 12 12h424c6.6 0 12-5.4 12-12z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>04. Apr. 2023<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-d102256 elementor-inline-item\" itemprop=\"about\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"icon icon-tag\"><\/i>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-terms\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-post-info__terms-list\">\n\t\t\t\t<a href=\"https:\/\/sfb1436.de\/de\/category\/publikation\/a06-de\/\" class=\"elementor-post-info__terms-list-item\">A06<\/a>\t\t\t\t<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-10759525 elementor-widget elementor-widget-heading\" data-id=\"10759525\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\"><a class=\"sfb-doi-link swiper-no-swiping\" href=\"https:\/\/doi.org\/10.1007\/s00702-023-02618-5\" target=\"_blank\" rel=\"noopener noreferrer\">Repurposing drugs against Alzheimer&#8217;s disease: can the anti-multiple sclerosis drug fingolimod (FTY720) effectively tackle inflammation processes in AD?<\/a><\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d46d3e7 elementor-widget elementor-widget-theme-post-content\" data-id=\"2d46d3e7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"theme-post-content.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n<p class=\"wp-block-paragraph\"><em>Volkmar Le\u00dfmann, Georgia-Ioanna Kartalou, Thomas Endres, Marc Pawlitzki, Kurt Gottmann <\/em><\/p>\n\n\n\n<div class=\"wp-block-uagb-icon-list uagb-block-98a378ce uagb-icon-list__outer-wrap uagb-icon-list__layout-vertical\"><div class=\"uagb-icon-list__wrap\">\n<div class=\"wp-block-uagb-icon-list-child uagb-block-07eba497 uagb-icon-list-repeater uagb-icon-list__wrapper\"><span class=\"uagb-icon-list__source-wrap\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 384 512\"><path d=\"M256 0v128h128L256 0zM224 128L224 0H48C21.49 0 0 21.49 0 48v416C0 490.5 21.49 512 48 512h288c26.51 0 48-21.49 48-48V160h-127.1C238.3 160 224 145.7 224 128zM272 416h-160C103.2 416 96 408.8 96 400C96 391.2 103.2 384 112 384h160c8.836 0 16 7.162 16 16C288 408.8 280.8 416 272 416zM272 352h-160C103.2 352 96 344.8 96 336C96 327.2 103.2 320 112 320h160c8.836 0 16 7.162 16 16C288 344.8 280.8 352 272 352zM288 272C288 280.8 280.8 288 272 288h-160C103.2 288 96 280.8 96 272C96 263.2 103.2 256 112 256h160C280.8 256 288 263.2 288 272z\"><\/path><\/svg><\/span><span class=\"uagb-icon-list__label\"><strong>J Neural Transm (2023)<\/strong><\/span><\/div>\n<\/div><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"28475\" class=\"elementor elementor-28475 swiper-slide e-loop-item e-loop-item-37866 post-37866 post type-post status-publish format-standard hentry category-a06-de category-b06-de category-c02-de tag-https-doi-org-10-3389-fncir-2021-659280-de\" data-elementor-post-type=\"elementor_library\" role=\"group\" aria-roledescription=\"slide\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-2dae7f0b custom-loop-item e-flex e-con-boxed e-con e-parent\" data-id=\"2dae7f0b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-32caa965 elementor-widget elementor-widget-post-info\" data-id=\"32caa965\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-7093930 elementor-inline-item\" itemprop=\"datePublished\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-calendar\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M12 192h424c6.6 0 12 5.4 12 12v260c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V204c0-6.6 5.4-12 12-12zm436-44v-36c0-26.5-21.5-48-48-48h-48V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H160V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H48C21.5 64 0 85.5 0 112v36c0 6.6 5.4 12 12 12h424c6.6 0 12-5.4 12-12z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>12. Juli 2021<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-d102256 elementor-inline-item\" itemprop=\"about\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"icon icon-tag\"><\/i>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-terms\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-post-info__terms-list\">\n\t\t\t\t<a href=\"https:\/\/sfb1436.de\/de\/category\/publikation\/a06-de\/\" class=\"elementor-post-info__terms-list-item\">A06<\/a>, <a href=\"https:\/\/sfb1436.de\/de\/category\/publikation\/b06-de\/\" class=\"elementor-post-info__terms-list-item\">B06<\/a>, <a href=\"https:\/\/sfb1436.de\/de\/category\/publikation\/c02-de\/\" class=\"elementor-post-info__terms-list-item\">C02<\/a>\t\t\t\t<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-10759525 elementor-widget elementor-widget-heading\" data-id=\"10759525\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\"><a class=\"sfb-doi-link swiper-no-swiping\" href=\"https:\/\/doi.org\/10.3389\/fncir.2021.659280\" target=\"_blank\" rel=\"noopener noreferrer\">Laser-Induced Apoptosis of Corticothalamic Neurons in Layer VI of Auditory Cortex Impact on Cortical Frequency Processing<\/a><\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d46d3e7 elementor-widget elementor-widget-theme-post-content\" data-id=\"2d46d3e7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"theme-post-content.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n<p class=\"wp-block-paragraph\"><em>Katja Saldeitis, Marcus Jeschke, Eike Budinger, Frank W Ohl, Max F K Happel<\/em><\/p>\n\n\n\n<div class=\"wp-block-uagb-icon-list uagb-block-cbf81e63 uagb-icon-list__outer-wrap uagb-icon-list__layout-vertical\"><div class=\"uagb-icon-list__wrap\">\n<div class=\"wp-block-uagb-icon-list-child uagb-block-a610db26 uagb-icon-list-repeater uagb-icon-list__wrapper\"><span class=\"uagb-icon-list__source-wrap\"><\/span><span class=\"uagb-icon-list__label\"><strong>Front Neural Circuits (2021)<\/strong><\/span><\/div>\n<\/div><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"28475\" class=\"elementor elementor-28475 swiper-slide e-loop-item e-loop-item-15544 post-15544 post type-post status-publish format-standard hentry category-a01-de category-a06-de tag-https-doi-org-10-1038-s41398-021-01365-z-de\" data-elementor-post-type=\"elementor_library\" role=\"group\" aria-roledescription=\"slide\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-2dae7f0b custom-loop-item e-flex e-con-boxed e-con e-parent\" data-id=\"2dae7f0b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-32caa965 elementor-widget elementor-widget-post-info\" data-id=\"32caa965\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-7093930 elementor-inline-item\" itemprop=\"datePublished\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-calendar\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M12 192h424c6.6 0 12 5.4 12 12v260c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V204c0-6.6 5.4-12 12-12zm436-44v-36c0-26.5-21.5-48-48-48h-48V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H160V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H48C21.5 64 0 85.5 0 112v36c0 6.6 5.4 12 12 12h424c6.6 0 12-5.4 12-12z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>22. Apr. 2021<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-d102256 elementor-inline-item\" itemprop=\"about\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"icon icon-tag\"><\/i>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-terms\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-post-info__terms-list\">\n\t\t\t\t<a href=\"https:\/\/sfb1436.de\/de\/category\/publikation\/a01-de\/\" class=\"elementor-post-info__terms-list-item\">A01<\/a>, <a href=\"https:\/\/sfb1436.de\/de\/category\/publikation\/a06-de\/\" class=\"elementor-post-info__terms-list-item\">A06<\/a>\t\t\t\t<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-10759525 elementor-widget elementor-widget-heading\" data-id=\"10759525\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\"><a class=\"sfb-doi-link swiper-no-swiping\" href=\"https:\/\/doi.org\/10.1038\/s41398-021-01365-z\" target=\"_blank\" rel=\"noopener noreferrer\">BDNF haploinsufficiency induces behavioral endophenotypes of schizophrenia in male mice that are rescued by enriched environment<\/a><\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d46d3e7 elementor-widget elementor-widget-theme-post-content\" data-id=\"2d46d3e7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"theme-post-content.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n<p class=\"wp-block-paragraph\">Mahmoud Harb, Justina Jagusch, Archana Durairaja, Thomas Endres, Volkmar Le\u00dfmann &amp; Markus Fendt&nbsp;<\/p>\n\n\n\n<div class=\"wp-block-uagb-icon-list uagb-block-4e629575 uagb-icon-list__outer-wrap uagb-icon-list__layout-vertical\"><div class=\"uagb-icon-list__wrap\">\n<div class=\"wp-block-uagb-icon-list-child uagb-block-e3e23bc4 uagb-icon-list-repeater uagb-icon-list__wrapper\"><span class=\"uagb-icon-list__source-wrap\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 384 512\"><path d=\"M256 0v128h128L256 0zM224 128L224 0H48C21.49 0 0 21.49 0 48v416C0 490.5 21.49 512 48 512h288c26.51 0 48-21.49 48-48V160h-127.1C238.3 160 224 145.7 224 128zM272 416h-160C103.2 416 96 408.8 96 400C96 391.2 103.2 384 112 384h160c8.836 0 16 7.162 16 16C288 408.8 280.8 416 272 416zM272 352h-160C103.2 352 96 344.8 96 336C96 327.2 103.2 320 112 320h160c8.836 0 16 7.162 16 16C288 344.8 280.8 352 272 352zM288 272C288 280.8 280.8 288 272 288h-160C103.2 288 96 280.8 96 272C96 263.2 103.2 256 112 256h160C280.8 256 288 263.2 288 272z\"><\/path><\/svg><\/span><span class=\"uagb-icon-list__label\"><strong>Translational Psychiatry (2021)<\/strong><\/span><\/div>\n<\/div><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<div class=\"elementor-swiper-button elementor-swiper-button-prev\" role=\"button\" tabindex=\"0\" aria-label=\"Voriger\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-eicon-chevron-left\" viewBox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M646 125C629 125 613 133 604 142L308 442C296 454 292 471 292 487 292 504 296 521 308 533L604 854C617 867 629 875 646 875 663 875 679 871 692 858 704 846 713 829 713 812 713 796 708 779 692 767L438 487 692 225C700 217 708 204 708 187 708 171 704 154 692 142 675 129 663 125 646 125Z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t\t<div class=\"elementor-swiper-button elementor-swiper-button-next\" role=\"button\" tabindex=\"0\" aria-label=\"N\u00e4chster\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-eicon-chevron-right\" viewBox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M696 533C708 521 713 504 713 487 713 471 708 454 696 446L400 146C388 133 375 125 354 125 338 125 325 129 313 142 300 154 292 171 292 187 292 204 296 221 308 233L563 492 304 771C292 783 288 800 288 817 288 833 296 850 308 863 321 871 338 875 354 875 371 875 388 867 400 854L696 533Z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t\t\t\t<div class=\"swiper-pagination\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0482d4f e-flex e-con-boxed e-con e-parent\" data-id=\"0482d4f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9c48a42 elementor-widget elementor-widget-eael-creative-button\" data-id=\"9c48a42\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-creative-button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t        <div class=\"eael-creative-button-wrapper\">\n\n            <a class=\"eael-creative-button eael-creative-button--default eael-cb-icon-position-\" href=\"https:\/\/sfb1436.de\/publications\/\" data-text=\"\">\n            \t    \n                <div class=\"creative-button-inner\">\n\n                    \n                    <span class=\"cretive-button-text\">Alle Publikationen<\/span>\n\n                                    <\/div>\n\t                        <\/a>\n        <\/div>\n        \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b69fd73 elementor-widget elementor-widget-eael-creative-button\" data-id=\"b69fd73\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-creative-button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t        <div class=\"eael-creative-button-wrapper\">\n\n            <a class=\"eael-creative-button eael-creative-button--default eael-cb-icon-position-\" href=\"https:\/\/sfb1436.de\/projects\/\" data-text=\"\">\n            \t    \n                <div class=\"creative-button-inner\">\n\n                    \n                    <span class=\"cretive-button-text\">Alle Projekte<\/span>\n\n                                    <\/div>\n\t                        <\/a>\n        <\/div>\n        \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>A06 Die flexible Steuerung von Verhalten und Verhaltens\u00e4nderungen durch Lernprozesse erfordert die neuronale Interaktion verschiedener Hirnareale. Die Interaktionen zwischen sensorischen und pr\u00e4frontalen Cortex-Arealen mit dem Hippocampus haben f\u00fcr diese Prozesse eine hervorgehobene Bedeutung. Wir untersuchen in unserem Projekt, wie durch Krankheit oder Altern bedingte St\u00f6rungen in einem der interagierenden Hirnareale durch neuroplastische Prozesse in den [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":24930,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-33786","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>BDNF-abh\u00e4ngige Neuroplastizit\u00e4t als neuronale Ressource der kortiko-hippokampalen Interaktion - SFB1436<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sfb1436.de\/de\/projekte\/archiv-sfb-1436-1-2021-2024\/bdnf-abhaengige-neuroplastizitaet-als-neuronale-ressource-der-kortiko-hippokampalen-interaktion\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"BDNF-abh\u00e4ngige Neuroplastizit\u00e4t als neuronale Ressource der kortiko-hippokampalen Interaktion - SFB1436\" \/>\n<meta property=\"og:description\" content=\"A06 Die flexible Steuerung von Verhalten und Verhaltens\u00e4nderungen durch Lernprozesse erfordert die neuronale Interaktion verschiedener Hirnareale. Die Interaktionen zwischen sensorischen und pr\u00e4frontalen Cortex-Arealen mit dem Hippocampus haben f\u00fcr diese Prozesse eine hervorgehobene Bedeutung. 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SFB1436","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/sfb1436.de\/de\/projekte\/archiv-sfb-1436-1-2021-2024\/bdnf-abhaengige-neuroplastizitaet-als-neuronale-ressource-der-kortiko-hippokampalen-interaktion\/","og_locale":"de_DE","og_type":"article","og_title":"BDNF-abh\u00e4ngige Neuroplastizit\u00e4t als neuronale Ressource der kortiko-hippokampalen Interaktion - SFB1436","og_description":"A06 Die flexible Steuerung von Verhalten und Verhaltens\u00e4nderungen durch Lernprozesse erfordert die neuronale Interaktion verschiedener Hirnareale. 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