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Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer’s disease
K. M Grochowska, G. M Gomes, R. Raman, R. Kaushik, L. Sosulina, H. Kaneko, A. M Oelschlegel, P. Yuanxiang, I. Reyes-Resina, G. Bayraktar, S. Samer, C. Spilker, M. S Woo, M. Morawski, J. Goldschmidt, M. A Friese, S. Rossner, G. Navarro, S. Remy, C. Reissner, A. Karpova, M. R Kreutz
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The needs of a synapse-How local organelles serve synaptic proteostasis
Katarzyna M Grochowska, Maria Andres-Alonso, Anna Karpova, Michael R Kreutz
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Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer’s disease
Alessandro Dario Confettura, Eleonora Cuboni, Mohamed Rafeet Ammar, Shaobo Jia, Guilherme M Gomes, PingAn Yuanxiang, Rajeev Raman, Tingting Li , Katarzyna M Grochowska, Robert Ahrends, Anna Karpova, Alexander Dityatev, Michael R Kreutz
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Jacob, a Synapto-Nuclear Protein Messenger Linking N-methyl-D-aspartate Receptor Activation to Nuclear Gene Expression
Katarzyna M Grochowska, Julia Bär, Guilherme M Gomes, Michael R Kreutz, Anna Karpova
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Molecular Mechanisms of Memory Consolidation That Operate During Sleep
Irene Reyes-Resina, Sebastian Samer, Michael R Kreutz, Anja M Oelschlegel
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Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment
Maximilian Borgmeyer, Cristina Coman, Canan Has, Hans-Frieder Schött, Tingting Li, Philipp Westhoff, Yam F H Cheung, Nils Hoffmann, PingAn Yuanxiang, Thomas Behnisch, Guilherme M Gomes, Mael Dumenieu, Michaela Schweizer, Michaela Chocholoušková, Michal Holčapek, Marina Mikhaylova, Michael R Kreutz, Robert Ahrends
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Autism-associated SHANK3 missense point mutations impact conformational fluctuations and protein turnover at synapses
Michael Bucher, Stephan Niebling, Yuhao Han, Dmitry Molodenskiy, Fatemeh Hassani Nia, Hans-Jürgen Kreienkamp, Dmitri Svergun, Eunjoon Kim, Alla S Kostyukova, Michael R Kreutz, Marina Mikhaylova
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The nuclear lamina is a hub for the nuclear function of Jacob
Sebastian Samer, Rajeev Raman, Gregor Laube, Michael R. Kreutz & Anna Karpova