CRC 1436 – Neural Resources of Cognition

Unlocking the Full Cognitive Potential of the Brain

How can the brain’s cognitive potential be mobilized, enhanced and maintained? An interdisciplinary team from the fields of medicine, biology, biochemistry, psychology, physics, and pharmacology is investigating these questions in the DFG-funded Collaborative Research Center (CRC) 1436 “Neural Resources of Cognition”.

New Fellows
The selection process for the MD Fellowship applications for the winter semester is now complete. We are pleased to announce that from October 2022 to September 2023, the IRTG will …

Research Area A

What are the molecular and synaptic
foundations for cognitive enhancement?

Research Area B

How does cognitive training change
the neural circuitry of the brain?

Research Area C

Are changes in the neural networks of the brain
related to the mobilization of cognitive resources?

News from the neurosciences of the CRC

New Fellows

The selection process for the MD Fellowship applications for the winter semester is now complete. We are pleased to announce that from October 2022 to September 2023, the IRTG will …
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We are pleased to announce that our first Outstanding Women in Neuroscience (OWN) – Award, presented by Prof. Carol Barnes, will be given to Dr. Anne Maaß. Congratulations!
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To mark World Alzheimer’s Day today, the DZNE is sharing an exciting video message about its research, which includes parts of CRC 1436.
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Today is World Alzheimer’s Day!

The University of Magdeburg posts on its Instagram account about the research in CRC 1436 project A05: Scientists at the University of Magdeburg and the Leibniz Institute for Neurobiology are …
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Latest research on WORLD ALZHEIMER’S DAY

The online magazine of Otto-von-Guericke University Magdeburg presents our CRC project A05 on today’s World Alzheimer’s Day. Prof. Constanze Seidenbecher explains her research in an interview.
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Neuroscientists support the Little Victories Ride

Neuroscientists at the University Hospital Magdeburg support the Little Victories Ride from Berlin to Brussels with the goal of advancing research in the fight against Parkinson’s disease and other neurodegenerative …
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PostDoc wanted

The SFB project A01 is offering a Postdoctoral position in molecular and behavioral neuroscience.
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Participants wanted

We are looking for motivated seniors who enjoy exercise. As part of a large project, we would like to investigate the influence of balance training on cognitive abilities.
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Our research focus

Is it possible to increase the performance of memory?
What is the hidden potential of the brain and what are its limits?
How can the brain’s cognitive potential be mobilized and enhanced?

The architecture of our brain provides biological limits for the performance of memory, attention, and our capacity for learning; this is evident on both the micro and macro scale. However, there is large variability within these limits and individual cognitive abilities can be improved through directed training. The goal of our Collaborative Research Center (CRC) is to uncover the performance limits of the human brain and to explore methodological approaches for improving this performance. We aim to understand which neurobiological principles limit cognitive resources and how these resources can be fully accessed or even enhanced. Further, we will identify new ways to preserve neural resources across the lifespan with targeted interventions.
More than 40 scientists in 22 individual projects are currently working in our CRC towards this exciting neuroscientific topic, which is also highly relevant in our current society.

Using the latest neuroscientific technologies and innovative methods, human and animal experimental studies will examine individual variability and transferable improvement in cognitive function. We place a specific focus on how performance improvements in one task can be transferred to other tasks and when task performance comes at the expense of other abilities. We also ask, why do cognitive abilities decline with age? And what are the tremendous resources of “super-agers”? Further, we are investigating how molecular and biochemical processes affect cognitive performance, for instance, with the deposition of tau and amyloid in the brain, or those that occur with sleep deprivation or other environmental influences. This project is funded by the German Research Foundation (DFG) and encompasses both the Otto von Guericke University Magdeburg and the Leibniz Institute of Neurobiology, as well as the German Center for Neurodegenerative Diseases (DZNE) Magdeburg site, Freie Universität Berlin, Charitè Universitätsmedizin Berlin, Forschungszentrum Jülich, and the universities of Düsseldorf, Heidelberg, and Göttingen.

Dr. Michael Kreutz & Prof. Dr. med. Emrah Düzel

Co-Spokesperson Dr. Michael Kreutz & Spokesperson Prof. Dr. med. Emrah Düzel

Publications of the CRC