CRC 1436 – Neural Resources of Cognition

Unlocking the Full Cognitive Potential of the Brain

How can the brain’s cognitive potential be mobilized, enhanced and maintained? An interdisciplinary team from the fields of medicine, biology, biochemistry, psychology, physics, and pharmacology is investigating these questions in the DFG-funded Collaborative Research Center (CRC) 1436 “Neural Resources of Cognition”.

Newly selected PhD representatives
Our IRTG is proud to announce that it has two newly elected PhD representatives. In an election with 33 participants, Anwesha Das and Martin Matke were elected. Both are the interdepartmental …

Research Area A

What are the molecular and synaptic
foundations for cognitive enhancement?

Research Area B

How does cognitive training change
the neural circuitry of the brain?

Research Area C

Are changes in the neural networks of the brain
related to the mobilization of cognitive resources?

News from the neurosciences of the CRC

Newly selected PhD representatives

Our IRTG is proud to announce that it has two newly elected PhD representatives. In an election with 33 participants, Anwesha Das and Martin Matke were elected. Both are the interdepartmental …
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Eike Budinger is apl.-Professor

Eike Budinger has been appointed apl. Professor. He received the certificate from Prof. Dr. Jens Strackeljan, the rector of Otto von Guericke University Magdeburg on June 24, 2021. This appointment honors …
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Our research focus

Is it possible to increase the performance of memory?
What is the hidden potential of the brain and what are its limits?
How can the brain’s cognitive potential be mobilized and enhanced?

The architecture of our brain provides biological limits for the performance of memory, attention, and our capacity for learning; this is evident on both the micro and macro scale. However, there is large variability within these limits and individual cognitive abilities can be improved through directed training. The goal of our Collaborative Research Center (CRC) is to uncover the performance limits of the human brain and to explore methodological approaches for improving this performance. We aim to understand which neurobiological principles limit cognitive resources and how these resources can be fully accessed or even enhanced. Further, we will identify new ways to preserve neural resources across the lifespan with targeted interventions.
More than 40 scientists in 22 individual projects are currently working in our CRC towards this exciting neuroscientific topic, which is also highly relevant in our current society.

Using the latest neuroscientific technologies and innovative methods, human and animal experimental studies will examine individual variability and transferable improvement in cognitive function. We place a specific focus on how performance improvements in one task can be transferred to other tasks and when task performance comes at the expense of other abilities. We also ask, why do cognitive abilities decline with age? And what are the tremendous resources of “super-agers”? Further, we are investigating how molecular and biochemical processes affect cognitive performance, for instance, with the deposition of tau and amyloid in the brain, or those that occur with sleep deprivation or other environmental influences. This project is funded by the German Research Foundation (DFG) and encompasses both the Otto von Guericke University Magdeburg and the Leibniz Institute of Neurobiology, as well as the German Center for Neurodegenerative Diseases (DZNE) Magdeburg site, Freie Universität Berlin, Charitè Universitätsmedizin Berlin, Forschungszentrum Jülich, and the universities of Düsseldorf, Heidelberg, and Göttingen.

Dr. Michael Kreutz & Prof. Dr. med. Emrah Düzel

Dr. Michael Kreutz & Prof. Dr. med. Emrah Düzel

Publications of the CRC

Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment

Maximilian Borgmeyer, Cristina Coman, Canan Has, Hans-Frieder Schött, Tingting Li, Philipp Westhoff, Yam F H Cheung, Nils Hoffmann, PingAn Yuanxiang, Thomas Behnisch, Guilherme M Gomes, Mael Dumenieu, Michaela Schweizer, Michaela Chocholoušková, Michal Holčapek, Marina Mikhaylova, Michael R Kreutz, Robert Ahrends Cell Rep (2021)