CRC 1436 – Neural Resources of Cognition

Unlocking the Full Cognitive Potential of the Brain

How can the brain’s cognitive potential be mobilized, enhanced and maintained? An interdisciplinary team from the fields of medicine, biology, biochemistry, psychology, physics, and pharmacology is investigating these questions in the DFG-funded Collaborative Research Center (CRC) 1436 “Neural Resources of Cognition”.

Research Area A

What are the molecular and synaptic
foundations for cognitive enhancement?

Research Area B

How does cognitive training change
the neural circuitry of the brain?

Research Area C

Are changes in the neural networks of the brain
related to the mobilization of cognitive resources?

News from the neurosciences of the CRC

CRC Writing Retreat at the Baltic Sea

On December 12th, 2022, 21 CRC members made their way to the Baltic Sea to devote a week entirely on writing. Among them are project leaders, PostDocs and PhD students,…

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CRC PI Markus Ullsperger honored

Markus Ullsperger received the award for his internationally outstanding research achievements in the field of neuronal decision processes.We sincerely congratulate! https://youtu.be/UGAem4BGAxA Here you can read the complete article of the…

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Balance and Cognition – Second Open Lab Day

On November 15th our Sub-project C01 “Dynamic modeling of training-induced, response-optimised mobilisation of neural resources” opened their doors. In a small competition, all CRC members had the opportunity to try…

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First CRC Open lab day

On October 19th, 2022, the CRC1436 hosted its first open lab day. Our sup-project B03 – Grid cell integrity as a neural resource for navigation and episodic memory – kicked…

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Wie sich Bewegung auf
unser Gedächtnis auswirkt

Pressestelle der Universitätsmedizin Magdeburg Wissenschaftler:innen aus den Bereichen Neuro- und Sportwissenschaften der Otto-von-Guericke-Universität Magdeburg untersuchen im Rahmen einer Studie den Einfluss von Gleichgewichtstraining auf das Gedächtnis von älteren Menschen. Dafür…

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CRC General meeting 2022

On September 27th, our annual general meeting took place at the Leibniz Institute for Neurobiology. In addition to numerous scientists from our own ranks, a representative of the Ministry, Mr….

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Our research focus

Is it possible to increase the performance of memory?
What is the hidden potential of the brain and what are its limits?
How can the brain’s cognitive potential be mobilized and enhanced?

The architecture of our brain provides biological limits for the performance of memory, attention, and our capacity for learning; this is evident on both the micro and macro scale. However, there is large variability within these limits and individual cognitive abilities can be improved through directed training. The goal of our Collaborative Research Center (CRC) is to uncover the performance limits of the human brain and to explore methodological approaches for improving this performance. We aim to understand which neurobiological principles limit cognitive resources and how these resources can be fully accessed or even enhanced. Further, we will identify new ways to preserve neural resources across the lifespan with targeted interventions.
More than 40 scientists in 22 individual projects are currently working in our CRC towards this exciting neuroscientific topic, which is also highly relevant in our current society.

Using the latest neuroscientific technologies and innovative methods, human and animal experimental studies will examine individual variability and transferable improvement in cognitive function. We place a specific focus on how performance improvements in one task can be transferred to other tasks and when task performance comes at the expense of other abilities. We also ask, why do cognitive abilities decline with age? And what are the tremendous resources of “super-agers”? Further, we are investigating how molecular and biochemical processes affect cognitive performance, for instance, with the deposition of tau and amyloid in the brain, or those that occur with sleep deprivation or other environmental influences. This project is funded by the German Research Foundation (DFG) and encompasses both the Otto von Guericke University Magdeburg and the Leibniz Institute of Neurobiology, as well as the German Center for Neurodegenerative Diseases (DZNE) Magdeburg site, Freie Universität Berlin, Charitè Universitätsmedizin Berlin, Forschungszentrum Jülich, and the universities of Düsseldorf, Heidelberg, and Göttingen.

Dr. Michael Kreutz & Prof. Dr. med. Emrah Düzel

Co-Spokesperson Dr. Michael Kreutz & Spokesperson Prof. Dr. med. Emrah Düzel

Publications of the CRC